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These approaches may include the use of topical or systemic anti-inflammatory medications, such as corticosteroids [5, 6] and nonsteroidal anti-inflammatory drugs (NSAIDs) [6], immunosuppressive therapy with agents like methotrexate or cyclosporine (CsA) [7], administration of antiviral or antibacterial agents in cases of infectious causes [8], and in certain instances, surgical intervention to address complications or unresponsive cases

Similar thiol capping was also reported by several authors[31,32]

10.4049/jimmunol.141.8.2629 J

Also, recent reports suggested that those with pre-existing conditions such as diabetes, hypertension, and pulmonary, cardiac, and kidney diseases are at a higher risk of developing a severe infection [20,21,22]

The active ingredient is kept from breaking down in the gut by being wrapped in phospholipid vesicles, which makes it easier for cells to take in

de la Rosa VR et al., represents POxs structural versatility and hydrophilic characteristics, enabling it to successfully withstand protein adsorption, which adds to its antifouling qualities